SLU-PP-332
25mg · 99%+ Purity
Description
Buy SLU-PP-332 25mg ERR agonist exercise mimetic at 99%+ purity. Researched for endurance, fat oxidation, and metabolic benefits.
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Research & Science
Evidence-based information about this compound
Chemical Properties
Molecular Weight
446.50 g/mol
Also known as:
SLU-PP-332, ERR Agonist
SLU-PP-332 is a synthetic small molecule agonist of Estrogen-Related Receptors (ERRs), particularly ERRα, ERRβ, and ERRγ. Often called an "exercise mimetic," it was developed to activate the same metabolic pathways that are stimulated by physical exercise.
The compound was developed at Saint Louis University (hence "SLU" in the name) and represents a novel approach to modulating metabolism. ERRs are nuclear receptors that regulate genes involved in energy metabolism, mitochondrial biogenesis, and oxidative phosphorylation.
Research has shown SLU-PP-332 can enhance endurance and promote fat oxidation in animal models, making it of significant interest for metabolic and exercise physiology research.
SLU-PP-332 activates metabolic pathways through ERR agonism:
- ERR Activation: Binds to and activates all three estrogen-related receptors (ERRα, β, γ).
- Gene Transcription: Increases expression of genes involved in oxidative metabolism.
- Mitochondrial Biogenesis: Promotes creation of new mitochondria.
- Fatty Acid Oxidation: Enhances the breakdown of fats for energy.
- Muscle Fiber Adaptation: May promote oxidative muscle fiber characteristics.
SLU-PP-332's exercise-mimicking effects have been demonstrated in research:
- Endurance: Studies show significantly increased running endurance in mice.
- Fatigue Resistance: Animals treated with SLU-PP-332 showed delayed fatigue onset.
- Without Exercise: Effects occurred even in sedentary animals.
- Gene Expression: Activates exercise-associated gene programs.
These findings suggest SLU-PP-332 may recapitulate some benefits of exercise training.
Sources:
SLU-PP-332 shows significant metabolic effects:
- Fat Oxidation: Increases fatty acid oxidation in skeletal muscle.
- Mitochondria: Enhances mitochondrial content and function.
- Metabolic Genes: Upregulates PGC-1α and related metabolic regulators.
- Body Composition: May influence fat mass in animal studies.
The metabolic effects make it relevant to obesity and metabolic disease research.
Sources:
This information is provided for educational purposes only and is based on published scientific research. This product is intended for research use only.
