
Melanotan II Nasal Spray
15ml · 99%+ Purity
Description
Melanotan II is a melanocortin receptor agonist investigated for its role in melanogenesis and photoprotection pathways. This nasal spray formulation allows for convenient delivery in in vitro and in vivo tanning research models.
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Research & Science
Evidence-based information about this compound
Chemical Properties
CAS Number
121062-08-6
Molecular Formula
C50H69N15O9
Molecular Weight
1024.18 g/mol
Amino Acid Sequence
Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2
Also known as:
MT-2, Melanotan II, MT2 Nasal
Melanotan 2 Nasal Spray delivers the same synthetic melanocortin peptide through intranasal administration. This formulation provides a non-injectable option for research applications, with the nasal mucosa offering rapid absorption into systemic circulation.
The nasal delivery route may provide certain advantages for research purposes, including ease of administration and potentially more rapid onset of effects. Each spray delivers a measured dose for consistent administration.
MT-2 nasal spray contains the same cyclic heptapeptide structure as injectable formulations, maintaining its melanocortin receptor binding properties.
Intranasal Melanotan 2 works through melanocortin pathways:
- Melanocortin Binding: Activates MC1R, MC3R, MC4R, and MC5R receptors.
- Melanogenesis: Stimulates melanin production through MC1R activation.
- Rapid Absorption: Nasal mucosa provides quick systemic access.
- Central Effects: May access CNS through nasal-brain pathways.
- Systemic Distribution: Circulates to act on peripheral melanocortin receptors.
MT-2's effects on melanogenesis are well-documented:
- Melanin Production: Stimulates melanin synthesis in melanocytes.
- MC1R Activation: Primary receptor for tanning effects.
- UV Protection: Increased melanin may offer enhanced UV protection.
- Pigmentation: Can produce significant darkening of skin.
Nasal delivery provides an alternative route for tanning research.
Sources:
This information is provided for educational purposes only and is based on published scientific research. This product is intended for research use only.

