GHRP-6
5mg · 99%+ Purity
HPLC Tested
99%+ Purity
About Our Testing
Every batch is tested by our manufacturer using HPLC analysis. Per-batch third-party testing adds significant cost and delays that would be passed to customers.
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Description
GHRP-6 is a growth hormone releasing peptide primarily researched for its influence on GH secretion via ghrelin receptor activation. Studies indicate potential applications in lean body mass and muscle recovery mechanism research models.
Research Use Only: This product is intended for laboratory research purposes only. Not for human consumption.
Research & Science
Evidence-based information about this compound
Chemical Properties
CAS Number
87616-84-0
Molecular Formula
C46H56N12O6
Molecular Weight
873.01 g/mol
Amino Acid Sequence
His-D-Trp-Ala-Trp-D-Phe-Lys-NH2
Also known as:
Growth Hormone Releasing Peptide 6, GHRP6
GHRP-6 (Growth Hormone Releasing Peptide-6) is a synthetic hexapeptide with the sequence His-D-Trp-Ala-Trp-D-Phe-Lys-NH2. It was one of the first synthetic GH secretagogues developed and remains widely used in research.
GHRP-6 stimulates growth hormone release by binding to the ghrelin receptor (GHSR) in the pituitary gland. Unlike hexarelin, GHRP-6 also significantly stimulates appetite through ghrelin-like effects, which may be desirable or undesirable depending on research goals.
This peptide produces a robust but not excessive GH pulse, making it useful for studying the effects of physiological GH elevation.
GHRP-6 acts through several mechanisms:
- Ghrelin Receptor Agonism: Binds to GHSR-1a, the ghrelin receptor, on pituitary somatotrophs.
- Somatostatin Suppression: May suppress somatostatin release, removing GH inhibition.
- Hypothalamic Action: Stimulates GHRH release from hypothalamus.
- Appetite Stimulation: Activates hunger pathways through ghrelin-like action.
- Gastric Effects: Increases gastric motility and acid secretion.
GHRP-6's effects on GH release have been extensively studied:
- Pulsatile Release: Produces physiological GH pulses rather than sustained elevation.
- Synergy with GHRH: Combined with GHRH, produces synergistic GH release.
- Age Effects: Maintains efficacy in aging subjects with blunted natural GH release.
- Consistent Response: Shows less receptor desensitization than hexarelin.
GHRP-6 remains valuable for GH physiology research.
Sources:
GHRP-6's appetite effects have research applications:
- Ghrelin Mimetic: Mimics the appetite-stimulating effects of ghrelin.
- Caloric Intake: Studies show increased food consumption after administration.
- Gastric Function: Increases gastric motility and secretion.
- Cachexia Research: May have applications in wasting conditions research.
The appetite effects may be beneficial or limiting depending on research context.
Sources:
This information is provided for educational purposes only and is based on published scientific research. This product is intended for research use only.
