Selank Nasal Spray
15ml · 99%+ Purity
Description
Selank nasal spray allows for convenient delivery of this anxiolytic peptide, studied for its cognitive-enhancing and immunomodulatory effects via tuftsin pathway modulation. Researchers investigate Selank's potential applications in anxiety and stress-related models.
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Research & Science
Evidence-based information about this compound
Chemical Properties
Molecular Formula
C33H57N11O9
Molecular Weight
751.87 g/mol
Amino Acid Sequence
Thr-Lys-Pro-Arg-Pro-Gly-Pro
Also known as:
SELANK, Selank Spray, TP-7
Selank Nasal Spray delivers the synthetic heptapeptide anxiolytic through intranasal administration. This delivery method may offer advantages for its intended neurological effects by potentially providing more direct access to the central nervous system.
Selank is a tuftsin analog with an added Pro-Gly-Pro sequence, combining immunomodulatory effects with anxiolytic properties. The nasal route allows for rapid absorption and possible nose-to-brain transport through olfactory pathways.
This formulation has been widely used in clinical practice in Russia for anxiety and cognitive support.
Intranasal Selank acts through several mechanisms:
- GABA Modulation: Enhances GABA receptor sensitivity without direct binding.
- Serotonin Effects: Influences serotonergic neurotransmission.
- Enkephalin Metabolism: Inhibits enzymes that degrade enkephalins.
- Immune Function: Retains tuftsin's immunomodulatory properties.
- Rapid CNS Access: Nasal delivery may provide direct brain access.
Selank's anti-anxiety effects have been studied:
- Anxiety Reduction: Shows anxiolytic effects comparable to benzodiazepines without sedation.
- No Dependence: Does not produce tolerance or withdrawal.
- Stress Response: Modulates the stress response system.
- Gene Expression: Affects expression of 84 genes related to GABA signaling.
The anxiolytic effects make intranasal Selank valuable for stress research.
Sources:
This information is provided for educational purposes only and is based on published scientific research. This product is intended for research use only.
