BPC-157: Research Overview
BPC-157 (Body Protection Compound-157) is a synthetic peptide consisting of 15 amino acids. It's derived from a protein found in human gastric juice and has become one of the most extensively studied peptides in regenerative research.
Peptide Profile
| Property | Details |
|---|---|
| Full Name | Body Protection Compound-157 |
| Amino Acids | 15 |
| Sequence | Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val |
| Molecular Weight | 1419.53 g/mol |
| CAS Number | 137525-51-0 |
| Purity | 99%+ (HPLC verified) |
| Form | Lyophilized powder |
Origin and Discovery
BPC-157 was first isolated and characterized in the 1990s. It's a partial sequence of a naturally occurring protein called BPC (Body Protection Compound) found in human gastric juice. The "157" refers to the specific 15-amino acid fragment that demonstrated notable biological activity in research settings.
Chemical Structure
The amino acid sequence of BPC-157:
```
H-Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val-OH
```
Key structural features:
Research Applications
BPC-157 has been studied in numerous research contexts:
Tissue Research
Mechanism Research
In-Vitro Studies
Published Research
BPC-157 has been the subject of extensive research, with studies published in peer-reviewed journals examining:
*Note: All research has been conducted in laboratory settings. BPC-157 is not approved for human use.*
Reconstitution Guidelines
Standard Protocol
| Vial Size | BAC Water | Concentration |
|---|---|---|
| 5mg | 2ml | 2,500mcg/ml |
| 5mg | 1ml | 5,000mcg/ml |
| 10mg | 2ml | 5,000mcg/ml |
Procedure
Dosing Reference (Research)
Common research concentrations:
| Application | Typical Range |
|---|---|
| In-vitro studies | 10-100ng/ml |
| Cell culture | Variable |
| Tissue samples | Research-dependent |
Storage Requirements
Lyophilized (Pre-Reconstitution)
Reconstituted
Quality Indicators
Expected Appearance
Lyophilized:
Reconstituted:
Signs of Degradation
Handling Notes
Companion Research Peptides
BPC-157 is sometimes studied alongside:
Conclusion
BPC-157 remains one of the most actively researched peptides in the regenerative research field. Its stability and well-characterized structure make it suitable for various laboratory applications. As with all research peptides, BPC-157 is intended for laboratory research only and is not approved for human use.
Frequently Asked Questions
What is BPC-157 used for in research?
BPC-157 is used in laboratory research studying tissue regeneration, cellular signaling, growth factor interactions, and various biological mechanisms. It's a tool for understanding biological processes, not a therapeutic agent.
How should BPC-157 be stored?
Lyophilized BPC-157 should be stored in a freezer at -20°C for long-term storage (2+ years) or refrigerated at 2-8°C for shorter periods. Once reconstituted, store refrigerated and use within 4-6 weeks.
What makes BPC-157 stable?
BPC-157's 15-amino acid structure lacks disulfide bonds and has relatively simple folding, making it more stable than many peptides. Proper storage in lyophilized form further enhances stability.
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