AOD-9604: Research Overview
AOD-9604 (Advanced Obesity Drug) is a modified fragment of human growth hormone (hGH), specifically the C-terminal portion (amino acids 177-191) with an added tyrosine at the N-terminus. It was developed to isolate the metabolic effects of HGH from its growth-promoting properties.
Peptide Profile
| Property | Details |
|---|---|
| Full Name | AOD-9604 / Tyr-hGH Fragment 177-191 |
| Origin | Modified hGH fragment |
| Amino Acids | 16 |
| Molecular Weight | ~1815 g/mol |
| Purity | 99%+ (HPLC verified) |
| Form | Lyophilized powder |
Development Background
AOD-9604 was developed at Monash University in Australia during the 1990s. Researchers identified that the C-terminal region of growth hormone contained specific metabolic activity distinct from the growth-promoting regions.
Key development points:
Mechanism of Interest
Lipolytic Research
AOD-9604 research has focused on:
IGF-1 Independence
Unlike full hGH, AOD-9604 research has shown:
Research Applications
Metabolic Studies
Comparative Research
Cell Biology
Reconstitution Protocol
Standard Volumes
| Vial Size | BAC Water | Concentration |
|---|---|---|
| 2mg | 1ml | 2,000mcg/ml |
| 5mg | 2ml | 2,500mcg/ml |
Procedure
Storage Guidelines
Lyophilized
Reconstituted
Physical Properties
Lyophilized:
Reconstituted:
Related Research Compounds
| Compound | Relationship |
|---|---|
| hGH 176-191 | Similar fragment, no tyrosine |
| Full hGH | Parent molecule |
| Tesamorelin | GHRH analog (different mechanism) |
Conclusion
AOD-9604 provides researchers with a tool to study metabolic effects associated with the C-terminal region of growth hormone, independent of growth-promoting activity. Its well-characterized structure supports targeted metabolic research applications.
*AOD-9604 is sold for research purposes only and is not approved for human use.*
Frequently Asked Questions
What makes AOD-9604 different from growth hormone?
AOD-9604 is only a small fragment (amino acids 177-191) of the full growth hormone molecule, plus an added tyrosine. It lacks the growth-promoting regions and does not stimulate IGF-1, allowing study of metabolic effects in isolation.
What does AOD stand for?
AOD stands for 'Advanced Obesity Drug,' reflecting the original research focus on metabolic and weight-related effects of this hGH fragment.
How should AOD-9604 be stored?
Store lyophilized AOD-9604 in a freezer at -20°C for long-term storage. Once reconstituted, refrigerate at 2-8°C and use within 4-6 weeks. Never freeze reconstituted solution.
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